A SIMPLE AND PRACTICAL SYNTHESIS OF METHYL BENZO[b]FURAN-3-CARBOXYLATES

作者：Melkonyan Ferdinand S^*; Golantsov Nikita E; Karchava Alexander V

来源：Heterocycles, 2008, 75(12): 2973-2980.

• Benzo[b]furan
• Copper-Catalyzed Reaction
• Ring Closure
• C-O Bond Formation
• Iron-Catalyzed Reaction

A simple and practical two-step procedure for the preparation of 2-unsubstituted 1-benzo[b]furan-3-carboxylic acid methyl esters is described. The procedure uses the copper-catalyzed intramolecular C-O bond formation and provides an efficient route to the title compounds in good to excellent yields.

• 出版日期2008-12-1