A herbal formula Erchen decoction for non-alcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials

作者：Li Wanshu; Wu Yan; Ge Wenzai; Fan Li; Sun Wei^*

来源：International Journal of Clinical and Experimental Medicine, 2017, 10(6): 9110-9116.

• Erchen decoction
• non-alcoholic fatty liver disease
• meta-analysis

Background and objective: Erchen Decoction (ECD) is a traditional Chinese medicinal formula, which is often used in the treatment of a variety of diseases. This systematic review aims to evaluate the efficacy of ECD in treating non-alcoholic fatty liver (NAFLD) disease according to the PRISMA systematic review standard. Methods: English and Chinese databases were searched from database inception to February 2017 without language restriction. Results: Seven RCTs with 1951 participants were included. Patients receiving ECD with conventional treatment showed a signi.cant increase in clinical improvement, compared with participants receiving conventional treatment alone (RR=1.25, 95% CI: 1.13 to 1.38, P<0.00001, I-2=54%). Conclusion: Although a consistent result that ECD might be more effective than conventional treatment in treating NAFLD in this study, further RCTs of higher quality, larger scale and longer follow-up periods are still required to identify the efficacy of ECD.

• 出版日期2017
• 单位温州医科大学