Utility of Fibroscan (R) in the evaluation of liver fibrosis

作者：Carrion Jose A^*

来源：Gastroenterologia y Hepatologia, 2009, 32(6): 415-423.

DOI：10.1016/j.gastrohep.2009.01.178

• Elastography
• Fibroscan
• Non-invasive
• Liver fibrosis

Chronic Liver diseases produce a progressive accumulation of collagenous fiber in the Liver parenchyma. For years, liver biopsy has been the gold standard to quantify liver fibrosis. Currently, non-invasive alternatives are available to quantify fibrosis. Transient elastography (TE) or Fibroscan (R) quantifies liver rigidity, which is proportional to the grade of liver fibrosis. Studies are available that have evaluated the reliability and limitations of TE in healthy individuals, in patients with acute hepatitis, in distinct chronic liver diseases and in liver transplant recipients. TE is reliable for the diagnosis of liver cirrhosis (F4) and significant fibrosis (F >= 2) but its values may vary according to the patient's characteristics and the etiology of the disease. TE can avoid liver biopsy in 90% of patients with cirrhosis and in up to 70% of those with significant fibrosis when combined with other non-invasive methods.

• 出版日期2009-7