Differential pulse anodic stripping voltammetric determination of berberine using a nano-Na-montmorillonite clay-modified carbon paste electrode

作者：Chen, Wen; Zhang, Ming-Xiao^*; Li, Cong; Li, Yong-Ling

来源：Journal of the Serbian Chemical Society, 2013, 78(4): 537-548.

DOI：10.2298/JSC120527093C

• berberine
• nano-Na-montmorillonite clay
• carbon paste electrode
• modified electrode
• electrochemical determination

A simple and sensitive method is presented for the electrochemical determination of berberine based on a nano-Na-montmorillonite (nano-Na-MMT) clay-modified carbon paste electrode. The electrochemical oxidation and adsorption behavior of berberine was studied at the proposed electrode by linear sweep voltammetry in acetate buffer (0.2 M, pH 5.6). A differential pulse anodic stripping voltammetric procedure was developed for the determination of the drug. A good linear relationship between the oxidation peak current magnitude and the concentration of berberine was observed in the range from 1.0 to 18.0 mu g mL(-1) with a detection limit of 0.07 mu g mL(-1) and a quantification limit of 0.24 mu g mL(-1). The proposed method was successfully applied to the determination of berberine in pharmaceutical tablets.

• 出版日期2013
• 单位西南大学