Detection of DNA base variation and cytosine methylation at a single nucleotide site using a highly sensitive fluorescent probe

作者:Duprey Jean Louis H A; Zhao Zheng yun; Bassani Dario M; Manchester Jack; Vyle Joseph S; Tucker James H R*
来源:Chemical communications, 2011, 47(23): 6629-6631.
DOI:10.1039/c1cc11205h

摘要

A fluorescent DNA probe containing an anthracene group attached via an anucleosidic linker can identify all four DNA bases at a single site as well as the epigenetic modification C/5-MeC via a hybridisation sensing assay.

  • 出版日期2011