A Palladium(II)-Catalyzed Synthesis of alpha-Ketoamides via Chemoselective Aroyl Addition to Cyanamides

作者：Guin Srimanta; Rout Saroj Kumar; Gogoi Anupal; Ali Wajid; Patel Bhisma K^*

来源：Advanced Synthesis & Catalysis, 2014, 356(11-12): 2559-2565.

DOI：10.1002/adsc.201400011

• chemoselectivity
• decarboxylation
• alpha-ketoamides
• palladium catalysis

An acyl moiety generated from alpha-oxocarboxylic acids via decarboxylation undergoes a palladium-catalyzed chemoselective insertion into organic cyanamides to afford N-monosubstituted alpha-keto-amides.

• 出版日期2014-8-11