Structural-functional evaluation of ionic liquid libraries for the design of co-solvents in lipase-catalysed reactions

作者:Rodrigues Joao V*; Ruivo Diana; Rodriguez Ana; Deive Francisco J; Esperanca Jose M S S; Marrucho Isabel M; Gomes Claudio M; Rebelo Luis Paulo N
来源:Green Chemistry, 2014, 16(10): 4520-4523.
DOI:10.1039/c4gc01329h

摘要

Using ionic liquids as co-solvents may improve reaction media in enzyme-based biotechnological processes. To establish new conditions, large libraries need to be screened for bio-compatibility and protein stabilisation. Using a lipase model, we herein describe a combination of methods leading to an expedited evaluation of 61 different solvent compositions.

  • 出版日期2014-10