Agarofuran sesquiterpenes from Schaefferia argentinensis

作者：Garcia Manuela E; Motrich Ruben D; Caputto Beatriz L; Sanchez Marianela; Palermo Jorge A; Estevez Braun Ana^*; Ravelo Angel G; Nicotra Viviana E

来源：Phytochemistry, 2013, 94: 260-267.

DOI：10.1016/j.phytochem.2013.06.003

• Schaefferia argentinensis
• Celastraceae
• Phytochemistry
• Antiproliferative activity
• Dihydro-beta-agarofuran sesquiterpene

Sixteen dihydro-beta-agarofuran sesquiterpenes were isolated from the aerial parts of Schaefferia argentinensis Speg. Their structures were determined by a combination of 1D and 2D NMR and MS techniques. The in vitro antiproliferative activity of the major sesquiterpenes was examined in T47D, MCF7, and MDA-MB231 human cancer cell lines, but was found to be marginal.

• 出版日期2013-10