A high-power laser-driven source of sub-nanosecond soft X-ray pulses for single-shot radiobiology experiments

作者：Davidkova Marie^*; Juha Libor; Bittner Michal; Koptyaev Sergey; Hajkova Vera; Krasa Josef; Pfeifer Miroslav; Stisova Viktorie; Bartnik Andrzej; Fiedorowicz Henryk; Mikolajczyk Janusz; Ryc Leszek; Pina Ladislav; Horvath Martin; Babankova Dagmar; Cihelka Jaroslav; Civis Svatopluk

来源：Radiation Research, 2007, 168(3): 382-387.

DOI：10.1667/RR0676.1

A large-scale, double-stream gas puff target has been illuminated by sub-kj, near-infrared (NIR) focused laser pulses at the PALS facility (Prague Asterix Laser System) to produce high-energy pulses of soft X rays from hot, dense plasma. The double-puff arrangement ensures high gas density and conversion efficiency from NIR to X rays approaching that typical for solid targets. In addition, its major advantage over solid targets is that it is free of debris and has substantially suppressed charged-particle emission. The X-ray emission characteristics of the source were determined for a range of gases that included krypton, xenon, N(2) CO and N(2),-CO. A demonstrated application of the xenon-based source is a single-shot damage induction to plasmid DNA. The yields of single-strand breaks (SSBs) and double-strand breaks (DSBs) were determined as a function of energy fluence adjusted by varying distance of sample from the source and thickness of aluminum filters.

• 出版日期2007-9