Use of an in vitro model in bovine to evidence a functional and molecular dialogue between preimplantation embryo and oviduct epithelial cells

作者：Cordova A; Perreau C; Schmaltz Panneau B; Locatelli Y; Ponsart C; Mermillod P^*

来源：Gynecologie Obstetrique & Fertilite, 2013, 41(9): 537-539.

DOI：10.1016/j.gyobfe.2013.07.015

• Embryo
• Coculture
• BOEC
• Oviduct
• Development

Beyond being a pipe between ovary and uterus, the oviduct is an active player in different aspects of early reproductive processes, in particular in the transport of embryos to the site of implantation and the regulation of its early development. Different studies evidenced a communication between oviduct and early embryo at the molecular and functional levels. Since the study of these interactions is difficult in vivo, different in vitro systems have been developed to mimic the maternal milieu during early development. These systems allowed to confirm the action of the cells on the quality of early development (blastocyst rate and viability). In turn, the embryos are producing signals that are able to modify and adapt the activity of maternal cells.

• 出版日期2013-9