General Last-Step Labeling of Biomolecule-Based Substrates by [C-12], [C-13], and [C-11] Carbon Monoxide

作者：Cornilleau Thomas; Audrain Helene; Guillemet Aude; Hermange Philippe^*; Fouquet Eric

来源：Organic Letters, 2015, 17(2): 354-357.

DOI：10.1021/ol503471e

Alkaloid-, steroid-, biotin-, carbohydrate-, nucleoside-, and peptide-based bioconjugates are easily labeled with CO by a last-step palladium-catalyzed carbonylation. The choice of the [C-12], [C-13], or [C-11] isotope opens the way to a new class of potential tracers or ligands easily available for various applications.

• 出版日期2015-1-16