Delphinidin prevents disuse muscle atrophy and reduces stress-related gene expression

作者：Murata Motoki; Kosaka Reia; Kurihara Kana; Yamashita Shuya; Tachibana Hirofumi^*

来源：Bioscience Biotechnology and Biochemistry, 2016, 80(8): 1636-1640.

DOI：10.1080/09168451.2016.1184560

• Delphinidin
• muscle atrophy
• Cbl-b

Delphinidin is a member of the anthocyanidin class of plant pigments. We examined the effects of delphinidin on muscle atrophy. Oral administration of delphinidin suppressed the muscle weight loss induced by mechanical unloading. Microarray analysis showed that delphinidin suppresses the upregulation of oxidative stress-related gene expression, including the expression of Cbl-b. Thus, delphinidin may prevent unloading-mediated muscle atrophy.

• 出版日期2016-8