The Relationship between Morning Hypertension and Sleep Quality in Patients with Obstructive Sleep Apnea Syndrome

作者：Sasaki Nobuo^*; Ozono Ryoji; Yamauchi Ryo; Teramen Kazushi; Edahiro Yoshinobu; Ishii Kiyomi; Seto Ayako; Kihara Yasuki

来源：Clinical and Experimental Hypertension, 2013, 35(4): 250-256.

DOI：10.3109/10641963.2013.780069

• obstructive sleep apnea syndrome
• morning hypertension
• sleep quality
• nocturnal hypertension
• morning surge

This study aimed to investigate the prevalence of abnormal diurnal blood pressure (BP) profiles in patients with obstructive sleep apnea syndrome (OSAS) in relation to the data of a sleep study. Total 103 patients newly diagnosed with OSAS underwent overnight polysomnography and 24-hour ambulatory BP measurements. Patients without morning or nocturnal hypertension (control group), patients with morning hypertension but not nocturnal hypertension (surge-type group), and patients with both morning and nocturnal hypertension (sustained-type group) were compared. Morning hypertension was present in 54 patients (16 surge-type and 38 sustained-type). The apnea-hypopnea index and sleep efficiency were higher and lower, respectively, in the sustained-type group than in the other groups. Slow-wave sleep incidence was significantly lower in the sustained-type and surge-type groups than in the control group. These results suggest that approximately half the OSAS patients displayed morning hypertension, the sustained-type being more common than the surge-type. Poor sleep quality plays an important role in the pathogenesis of morning hypertension in both the sustained- and the surge-type group.

• 出版日期2013