Acute Ataxia in Childhood: 11-Year Experience at a Major Pediatric Neurology Referral Center

作者：Thakkar Kavita^*; Maricich Stephen M; Alper Gulay

来源：Journal of Child Neurology, 2016, 31(9): 1156-1160.

DOI：10.1177/0883073816643407

• cerebellar ataxia
• case studies
• case series
• acute cerebellitis
• postinfectious cerebellar ataxia
• acute ataxia

We categorized the causes of acute ataxia in the pediatric populationreferred to the Division of Neurologyat a large, urban pediatric medical center. Of the 120 cases identified over the past 11 years, post-infectious cerebellar ataxia was the most commonly diagnosed (59%), followed by drug intoxication, opsoclonus-myoclonus ataxia syndrome, episodic ataxia, acute cerebellitis, cerebellar stroke, ADEM, meningitis, cerebral vein thrombosis, Leigh's disease, Miller-Fisher syndrome, and concussion. Among the patients with post-infectious cerebellar ataxia, 85% were 1-6 years old and all had a history of antecedent viral illness. CSF pleocytosis was present in 40% of patients; all had normal brain MRIs. The majority (91%) recovered within 30 days. We conclude that post-infectious cerebellar ataxia remains the most common cause of acute ataxia in childhood and that it carries a good prognosis. We also differentiate acute post-infectious cerebellar ataxia from other causes with similar presentations.

• 出版日期2016-8