Adipose derived stem cells: Isolation technique and application on surgery

作者：Meruane N Manuel; Rojas R Mariana

来源：Revista Chilena de Cirugia, 2011, 63(2): 223-228.

• Stem cells
• adipose tissue
• healing

Adipose derived stem cells: Isolation technique and application on surgery
Human wound healing requires multiple inflammatory cells, cytokines, growth factors and mesenchymal stem cells, which are found in almost all adult tissues, mainly in the bone marrow and adipose tissue. Has been shown multilineage differentiation capacity of these cells and their involvement in other processes by secreting paracrine factors. In the following review will discuss the technique to obtain and cultivate stem cells from liposuction adipose tissue, in addition to reviewing the publications in which they have been used to treat surgical diseases in humans. These include treatment of radiation scars, fractures, anal fistulas, soft tissue augmentation and organ transplantation. Now is included in surgery the concept of "regeneration" in addition to the traditional resection and healing. The results presented are favorable although more randomized studies are required.

• 出版日期2011-4