A novel graphene oxide-based fluorescent nanosensor for selective detection of Fe3 with a wide linear concentration and its application in logic gate

作者：He, Liang; Li, Jianna; Xin, John H^*

来源：Biosensors and Bioelectronics, 2015, 70: 69-73.

DOI：10.1016/j.bios.2015.01.075

• Graphene oxide
• Nanosensor
• Electron buffer
• Logic gate
• Cell imaging

A graphene oxide-based fluorescent nanosensor AGO has been designed and synthesized by covalent grafting allylamine onto GO surface. In aqueous media, AGO displays a highly selective and sensitive discrimination of Fe3 from Fe2 and other metal ions through electron transfer-induced fluorescence quenching. The quenching of AGO fluorescence is linearly proportional to Fe3 concentration in a wide range of 0-120 mu M (correlation coefficient R-2=0.9994). Moreover, AGO can be used to construct a combinational three-input logic gate to discriminate Fe3 and Fe2 . The logic gate works well in intracellular fluorescence imaging, which shows a potential as a promising platform for biosensing analysis.

• 出版日期2015-8-15
• 单位深圳大学; 香港理工大学