Anomalous J-Modulation Effects on Amino Acids in Clinical 3T MR Spectroscopy

作者:Liu, H S; Chung, H W; Juan, C J; Tsai, S Y; Wang, C Y; Chan, C C; Huang, G S; Chou, M C; Lee, C S; Ko, C W; Cho, N Y; Chen, C Y*
来源:American Journal of Neuroradiology, 2008, 29(9): 1644-1648.
DOI:10.3174/ajnr.A1131

摘要

The signal-intensity loss from anomalous J-modulation effects due to chemical-shift displacement was investigated on amino acid groups (alanine, valine, leucine, and isoleucine) at 3T by using point-resolved H-1 spectroscopy in patients with brain abscess and phantom experiments. With a larger chemical shift between methyl and methine resonances, alanine shows a greater effect of signal-intensity cancellation compared with other amino acids around 0.9 ppm, resulting in noninverted doublets at a TE of 144 ms.