Development of Cationic Polymer Coatings to Regulate Foreign-Body Responses

作者:Ma Minglin; Liu Wendy F; Hill Paulina S; Bratlie Kaitlin M; Siegwart Daniel J; Chin Justin; Park Miri; Guerreiro Joao; Anderson Daniel G*
来源:Advanced Materials, 2011, 23(24): H189-H194.
DOI:10.1002/adma.201100513

摘要

A library of cationic polymers, poly(beta-amino alcohols) with a great chemical diversity are synthesized using combinatorial polymerization. These polymers, when immobilized on a surface, drastically affect the behavior of monocyte/macrophage cells in vitro and early inflammatory reactions in vivo. Certain polymers are found capable of mitigating the foreign-body responses.

  • 出版日期2011-6-24