Novel triterpenoid saponins from the seeds of Celosia argentea L.

作者:Wu, Qing Bin; Wang, Yan; Liang, Lin; Jiang, Qian; Guo, Mei Li*; Zhang, Jun Jie
来源:Natural Product Research, 2013, 27(15): 1353-1360.
DOI:10.1080/14786419.2012.740034

摘要

Two new triterpenoid saponins celosin I (1) and celosin II (2) were isolated from the seeds of Celosia argentea L. (Amaranthaceae). The structures of the two new compounds were elucidated based on chemical analysis and spectral methods (IR, 1-D and 2-D NMR, ESI-MS, HR-ESI-MS). They exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.