Alcohol intake and risk of rosacea in US women

作者：Li, Suyun; Cho, Eunyoung; Drucker, Aaron M.; Qureshi, Abrar A.; Li, Wen-Qing^*

来源：Journal of the American Academy of Dermatology, 2017, 76(6): 1061-+.

DOI：10.1016/j.jaad.2017.02.040

• alcohol intake
• cohort studies
• dose-response relationship
• epidemiology
• rosacea
• smoking

Background: The epidemiologic association between alcohol and rosacea is unclear and inconsistent based on the previous cross-sectional or case-control studies. Objective: We conducted a cohort study to determine the association between alcohol intake and the risk of rosacea in women.
Methods: A total of 82,737 women were included from the Nurses' Health Study II (1991-2005). Information on alcohol intake was collected every 4 years during follow-up. Information on history of clinician-diagnosed rosacea and year of diagnosis was collected in 2005.
Results: Over 14 years of follow-up, we identified 4945 cases of rosacea. Compared with never drinkers, increased alcohol intake was associated with a significantly increased risk of rosacea (P-trend <. 0001). The multivariate-adjusted hazard ratios (HRs) and confidence intervals (CIs) were 1.12 (95% CI 1.05-1.20) for alcohol intake of 1-4 g/day and 1.53 (1.26-1.84) for >= 30 g/day. The associations remained consistent across categories of smoking status. Further examination of types of alcoholic beverage consumed revealed that white wine (P-trend < .0001) and liquor intake (P-trend = .0006) were significantly associated with a higher risk of rosacea.
Limitations: This was an epidemiologic study without examination into etiologic mechanisms.
Conclusions: Alcohol intake was significantly associated with an increased risk of rosacea in women.

• 出版日期2017-6
• 单位山东大学