科研之友
微信
新浪微博
Facebook
分享链接
摘要
The aim of this study was to investigate the role of soil and rice pollution on human renal dysfunction. The participants were 97 inhabitants (46 men and 51 women) who are aged 50 to 60 years old and have been living in Xiaogan (Hubei, China) from birth. We collected samples of soil, rice, and urinary correspondingly. Urinary N-acetyl-beta-D-glucosaminidase (NAG) and beta-2-microglobulin (beta(2)MG) were used as indicators of renal dysfunction, and urinary cadmium (U-Cd) was used as indicator of total internal cadmium exposure. We made a hypothesis that soil cadmium concentration (S-Cd) and rice cadmium concentration (R-Cd) could be used as indicators of environmental cadmium exposure. Correlation and path analysis were used to estimate the relationships among the levels of rice cadmium (R-Cd), soil cadmium (S-Cd), urinary cadmium (U-Cd), and renal damage indicators (NAG and beta(2)MG). Our results showed that there was positive significant relationship between S-Cd (R-Cd, U-Cd), and U-NAG (U-beta(2)MG). The standard multiple regression describing the relationship between S-Cd (R-Cd, U-Cd) and U-NAG was Y-1 = 1.26X(1)-6.53X(2) + 9.32, where Y is U-NAG, X-1 is U-Cd, X-2 is S-Cd. The equation of U-beta(2)MG was Y = 49.32X(1) + 3085.99X(2) + 143.42, where Y is U-beta(2)MG, X-1 is U-Cd, X-2 is R-Cd. It is obvious that the effect of S-Cd and R-Cd on NAG or U-beta(2)MG cannot be ignored. Through our study, we can find that the effects of S-Cd on renal health even as significant as R-Cd. To protect people from the damage of cadmium pollution, it is vital to monitor the situation of soil and rice cadmium pollution.
- 出版日期2017-1
- 单位北京交通大学
