FeSO4 center dot 7H(2)O-catalyzed oxidative amidation of methylarenes

作者：Karimi Meghdad; Saberi Dariush; Azizi Kobra; Ghonchepour Ehsan; Heydari Akbar^*

来源：Tetrahedron Letters, 2015, 56(21): 2674-2677.

DOI：10.1016/j.tetlet.2015.03.114

• Catalyst
• Oxidation
• Amidation
• Methylarenes
• tert-Butyl hydroperoxide

An efficient method has been described employing FeSO4 center dot 7H(2)O as a catalyst for the synthesis of amides from methylarenes and amines (hydrochloride salts) with tert-butyl hydroperoxide as an external oxidant. Primary, secondary, and tertiary amides were synthesized in moderate to good yields. A variety of amines and methylarenes were used to investigate the scope of this process.

• 出版日期2015-5-20