Alcohol use and mortality in older men and women

作者：McCaul Kieran A^*; Almeida Osvaldo P; Hankey Graeme J; Jamrozik Konrad; Byles Julie E; Flicker Leon

来源：Addiction, 2010, 105(8): 1391-1400.

DOI：10.1111/j.1360-0443.2010.02972.x

• Aged
• alcohol consumption
• cause of death
• cohort studies
• drinking patterns
• gender differences
• mortality

Aims
To compare the effect of alcohol intake on 10-year mortality for men and women over the age of 65 years.
Design, setting and participants
Two prospective cohorts of community-dwelling men aged 65-79 years at baseline in 1996 (n = 11 727) and women aged 70-75 years in 1996 (n = 12 432).
Measurements
Alcohol was assessed according to frequency of use (number of days alcohol was consumed per week) and quantity consumed per day. Cox proportional hazards models were compared for men and women for all-cause and cause-specific mortality.
Findings
Compared with older adults who did not consume alcohol every week, the risk of all-cause mortality was reduced in men reporting up to four standard drinks per day and in women who consumed one or two drinks per day. One or two alcohol-free days per week reduced this risk further in men, but not in women. Similar results were observed for deaths due to cardiovascular disease.
Conclusions
In people over the age of 65 years, alcohol intake of four standard drinks per day for men and two standard drinks per day for women was associated with lower mortality risk. For men, the risk was reduced further if accompanied with 1 or 2 alcohol-free days per week.

• 出版日期2010-8
• 单位河北医科大学