Diffusion-weighted imaging and positron emission tomography in various cytological subtypes of primary lung adenocarcinoma

作者：Tanaka Ryota^*; Nakazato Yoshimasa; Horikoshi Hiroyuki; Tsuchida Shigeru; Yoshida Tsutomu; Nakazato Yoko; Tachibana Keisei; Kondo Haruhiko; Goya Tomoyuki

来源：Clinical Imaging, 2013, 37(5): 876-883.

DOI：10.1016/j.clinimag.2013.06.001

• Magnetic resonance imaging
• Diffusion-weighted imaging
• Positron emission tomography
• Lung adenocarcinoma
• Cytological subtypes

The purpose of the study was to retrospectively characterize diffusion-weighted magnetic resonance imaging (DWI) and positron emission tomography for differentiating among the various cytological subtypes of primary lung adenocarcinomas. The maximum diffusion signal intensities and the maximum standardized uptake value (SUV max) of 31 lesions were analyzed after delineation of regions of interest on the images. Diffusion intensities were 0.934 for Clara type, 0.938 for type II type, 1.473 for nongoblet type, and 1.617 for poorly differentiated adenocarcinoma type based on Shimosato's cytological classification (P=.020). The SUV max values were 4.926, 5.491, 5.709, and 12.132, respectively (P=.044). DWI might reflect some of the cytological characteristics of the tumor cells for differentiating the subtypes of lung adenocarcinomas.

• 出版日期2013-10