A new 4-Amino-7-Nitro-2,1,3-Benzoxadiazole (ANBD)-Based Fluorescent Probe for the Detection of Hg2+

作者：Wang, Ke^*; Mao, Xue; Cao, Liling; Lv, Guoping; Dong, Xinfeng; He, Yan; Wei, Yongju^*

来源：Journal of Fluorescence, 2017, 27(5): 1739-1745.

DOI：10.1007/s10895-017-2112-4

• 4-amino-7-nitro-2,1,3-benzoxadiazole
• Fluorescent probe
• Hg2+
• Fluorescence enhancement

Based on the photoinduced electron transfer (PET) principle, 4-amino-7-nitro-2,1,3-benzoxadiazole (ANBD) has been used as a fluorophore to develop a new fluorescent probe, 4-(2-N,N-dimethylthioacetamide)amino-7-nitro-2,1,3-benzoxadiazole (2), for the detection of Hg2+. Upon the addition of Hg2+, a 46-fold fluorescence enhancement occurs. Moreover the probe 2 exhibits a high selectivity and sensitivity to Hg2+, even in the presence of other common metal ions. Under optimal reaction conditions, a good linearity can be obtained in the range of 0.5-2.5 mu M, and the detection limit is 0.05 mu M. In addition, the desulfurization reaction mechanism is proposed based on electrospray ionization mass spectrum. The present study is not only a supplement to the detection method of Hg2+, but also a merit to the development of ANBD-based fluorescent probes.

• 出版日期2017-9
• 单位河北师范大学