Deposition, structure, physical and invitro characteristics of Ag-doped beta-Ca-3(PO4)(2)/chitosan hybrid composite coatings on Titanium metal

作者：Singh Ram Kishore; Awasthi Sharad; Dhayalan Arunkumar; Ferreira J M F; Kannan S^*

来源：Materials Science and Engineering: C , 2016, 62: 692-701.

DOI：10.1016/j.msec.2016.02.013

• Silver
• beta-Ca-3(PO4)(2)
• Chitosan
• Composite
• Ti metal

Pure and five silver-doped (0-5Ag) beta-tricalcium phosphate [beta-TCP, beta-Ca-3(PO4)(2)]/chitosan composite coatings were deposited on Titanium (Ti) substrates and their properties that are relevant for applications in hard tissue replacements were assessed. Silver, beta-TCP and chitosan were combined to profit from their salient and complementary antibacterial and biocompatible features. The beta-Ca-3(PO4)(2) powders were synthesized by co-precipitation. The characterization results confirmed the Ag+ occupancy at the crystal lattice of beta-Ca-3(PO4)(2). The Ag-doped beta-Ca-3(PO4)(2)/chitosan composite coatings deposited by electrophoresis showed good antibacterial activity and exhibited negative cytotoxic effects towards the human osteosarcoma cell line MG-63. The morphology of the coatings was observed by SEM and their efficiency against corrosion of metallic substrates was determined through potentiodynamic polarization tests.

• 出版日期2016-5-1