Detection of single gold nanoparticles using spatial modulation spectroscopy implemented with a galvo-scanning mirror system

作者:Devadas Mary Sajini; Li Zhongming; Major Todd A; Lo Shun Shang; Havard Nicolas; Yu Kuai; Johns Paul; Hartland Gregory V*
来源:Applied Optics, 2013, 52(32): 7806-7811.
DOI:10.1364/AO.52.007806

摘要

The optical extinction of single nanoparticles can be sensitively detected by spatial modulation spectroscopy (SMS), where the particle is moved in and out of a tightly focused laser beam with a piezo-device. Here we show that high sensitivity can be obtained by modulating the beam with a galvo-mirror system, rather than by moving the sample. This work demonstrates an inexpensive method for making a SMS microscope, and shows how an existing laser scanning microscope can be adapted for SMS measurements. The galvo-mirror technique also allows SMS measurements to be performed in a liquid, which is difficult to do with piezo-modulation.

  • 出版日期2013-11-10