Diagnostic of the control and sensitivity profile of nematodes from sheep to albendazole and levamisole in northern Minas Gerais, Brazil

作者：Duarte Eduardo R^*; Silva Rayana B; Vasconcelos Viviane O; Nogueira Flavia A; Oliveira Neide J F

来源：Pesquisa Veterinaria Brasileira, 2012, 32(2): 147-152.

DOI：10.1590/S0100-736X2012000200010

• Albendazole
• levamisole
• anti-helminthics
• sheep
• resistance
• helminthosis
• semiarid

Duarte E.R., Silva R.B., Vasconcelos V.O., Nogueira F.A. %26 Oliveira N.J.F. 2012. [Diagnostic of the control and sensitivity profile of nematodes from sheep to albendazole and levamisole in northern Minas Gerais, Brazil.] Perfil de sensibilidade de nematodeos de ovinos ao albendazol e ao levamisol no norte de Minas Gerais. Pesquisa Veterinaria Brasileira 32(2): 147-152. Instituto de Ciencias Agrarias, Universidade Federal de Minas Gerais, Campus Regional de Montes Claros, Av. Universitaria 1000, Bairro Universitario, Montes Claros, MG 39404-006, Brazil. E-mail: [e-mail] %26lt;br%26gt;The anthelmintic resistance is a major obstacle for the nematode control in ruminants and the presence of multiresistant nematodes could make impracticable the activity in a given area. The objective in this study was to evaluate the anthelmintic efficacy of albendazole and levamisole in sheep herds in northern Minas Gerais. The test was performed on ten farms, where we selected three groups of 12 lambs each. Two of these groups were respectively treated with levamisole (5mg/kg) or albendazole (10mg/kg). The third group did not receive treatment. Feces were collected at 0 and 7 day after treatment for the fecal egg reduction test. The nematode genus was evaluated with the identification of the larvae obtained from culture in the feces pre- and post-treatments. For all evaluated herds the levamisole showed high anthelminthic efficacy, which ranged from 90 to 100%. Only for one herd, the albendazole was effective and for six farms, the efficacy of this drug was less than 80%, considered insufficiently active. After the cultivation of larvae were identified mainly Haemonchus spp. and Trichostrongylus spp. The genus Haemonchus was the most prevalent even after treatment of sheep. It is emphasized the importance of in vivo efficacy tests for choosing anthelmintic drugs, since the susceptibility profile varied among sheep herds evaluated in this study.

• 出版日期2012-2