A pox upon your house

作者：Hashemi Nafiseh; Zhang Jason; Volpi John; Lee Andrew G^*; Gordon Lynn K

来源：Survey of Ophthalmology, 2013, 58(6): 640-643.

DOI：10.1016/j.survophthal.2012.05.005

• herpes zoster sine herpete
• herpes zoster ophthalmicus
• uveomeningeal syndrome
• encephalitis
• cerebral infarction

Herpes zoster ophthalmicus (HZO) is a common viral infectious disorder affecting the ophthalmic division of the trigeminal nerve. A small subset of HZO patients present with the ophthalmic symptoms, but without an accompanied rash, a condition described as Herpes zoster sine herpete. Although HZO is well known to be associated with other central nervous system abnormalities, encephalitis and cerebral infarction are atypical and uncommon. We report an unusual case of presumed unilateral Herpes zoster ophthalmicus sine herpete that presented with trigeminal pain and uveitis and then progressed to encephalitis and bilateral cerebral infarctions despite treatment with acyclovir and corticosteroids. The diagnosis of HZV was confirmed by polymerase chain reaction testing on the cerebrospinal fluid.

• 出版日期2013-12