Postnatal expression pattern of the C/EBP alpha gene in porcine subcutaneous adipose tissue

作者：Jiang JF^*; Xu ZR; Wang YZ; Han XY; Wang L

来源：Journal of Animal and Feed Sciences, 2006, 15(1): 61-70.

• C/EBP alpha
• transcription factor
• gene expression
• fat deposition
• pigs

CCAAT/enhancer binding protein alpha (C/EBP alpha) has been implicated as a key regulator of adipocyte differentiation and lipid metabolism. The pattern of C/EBP alpha gene expression in different growth stages and its relation to adipose deposition was studied. Fifteen female Duroc x Landrace x Yorkshire pigs in five groups of three pigs each, weighing 1, 30, 50, 70 and 90 kg were used to study developmental gene expression of C/EBPa in subcutaneous adipose tissue by means of semi-quantitative RT-PCR. The results showed that the C/EBP alpha rnRNA levels in porcine adipose tissue continuously increased as the pigs grew and deposited fat from 1 to 90 kg body weight (BW) (P < 0.05). The presented data show a close positive correlation between the levels of C/EBP alpha gene expression and the fat deposition rate in pigs. The experiment showed that total adipose weight increased significantly with BW (P < 0.05).

• 出版日期2006
• 单位浙江大学