New insights into the mechanisms of action of radioimmunotherapy in lymphoma

作者:Ivanov Andrei; Swann Ruth; Illidge Tim*
来源:Journal of Pharmacy and Pharmacology, 2008, 60(8): 987-998.
DOI:10.1211/jpp.60.8.0006

摘要

The exquisite sensitivity of haematological malignancies to targeted radiation alongside the impressive results achieved by the pioneers in this field suggests that radioimmunotherapy is likely to be a productive area for future clinical research. Recent experimental work has demonstrated that the combination of targeted radiation and antibody effector mechanisms are critical to long-term clearance of tumour. This review provides the background of clinical and biological insights into the mechanisms of action of radioimmunotherapy.

  • 出版日期2008-8