A CONVENIENT SYNTHESIS OF 2-AMINO-1,3-SELENAZOLES USING IONIC LIQUID AND MICROWAVE IRRADIATION

作者：Maradolla Mohanbabu; Chandramouli G V P^*

来源：Phosphorus, Sulfur, and Silicon and the Related Elements, 2011, 186(8): 1650-1654.

DOI：10.1080/10426507.2010.527557

• [Bmim]BF4
• microwave irradiation
• selenazoles
• selenourea

A simple and environmentally benign synthesis of 2-amino-1,3-selenazoles by microwave irradiation using 1-butyl-3-methylimidazolium tetrafluoroborate ([Bmim]BF4) ionic liquid (IL) is described. Acyl halides, phenacyl halides, and alpha-bromo-beta-keto esters easily undergo condensation with selenourea in ([Bmim]BF4) by microwave irradiation to afford the desired products of good purity in excellent yields. The ionic liquid can be easily recovered and reused at least 10 times without losing its activity. The duration of the reaction ranges from 4-6 min.
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• 出版日期2011