A non-enzymatic glucose sensor based on the CuS nanoflakes-reduced graphene oxide nanocomposite

作者：Yan, Xiaoyi; Gu, Yue; Li, Cong; Zheng, Bo; Li, Yaru; Zhang, Tingting; Zhang, Zhiquan^*; Yang, Ming^*

来源：Analytical Methods, 2018, 10(3): 381-388.

DOI：10.1039/c7ay02290e

• HIGH-PERFORMANCE SUPERCAPACITOR
• LITHIUM ION BATTERIES
• ONE-POT SYNTHESIS
• ELECTROCHEMICAL DETECTION
• HYDROGEN-PEROXIDE
• OXYGEN REDUCTION
• CARBON ELECTRODE
• NANOPARTICLES
• COMPOSITES
• HYBRID

In this work, a copper sulfide nanoflakes-reduced graphene oxide (rGO/CuSNFs) nanocomposite has been successfully synthesized via one-pot hydrothermal treatment, where the reduction of GO and in situ generation of CuS nanoflakes occurred simultaneously. Subsequently, a nonenzymatic electrochemical sensor was fabricated based on the disposable rGO/CuSNFs nanocomposite for the highly sensitive and selective detection of glucose. The prepared rGO/CuSNFs nanocomposite was characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy-dispersive X-ray spectrometry (EDX), X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy, respectively. Under optimized conditions, the prepared enzymeless sensor exhibited remarkable catalytic activity toward the glucose oxidation with a fast response time of <6 s, a wide linear range from 1 to 2000 mM, a high sensitivity of 53.5 mu M (cm(2) mM)(-1) and a low detection limit of 0.19 mu M. Furthermore, the rGO/CuSNFs/GCE also showed the great reproducibility, the long-term storage stability and the excellent anti-interference ability for glucose sensing. In addition, the as-prepared sensor was applied to detect glucose in human urine and blood serum samples with satisfactory results, indicating that the rGO/CuSNFs nanocomposite is an extremely promising material for non-enzymatic glucose sensing in practical samples.

• 出版日期2018-1-21
• 单位吉林大学