科研之友
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摘要
This study presents a novel and precision process for fabricating a microneedle mold. The process includes a microlens array mask with contact printing in ultraviolet lithography. This method can precisely control the geometric profile of a microneedle array without the use of an etching process. The micro tapered cone microneedle mold utilizes the microlens array mask with geometrical optics. The light passes through the microlens and a hole in a Cr film of a mask, and then radiates onto the photoresist film. The light transmitted through the microlens has an aligned focal point on the photoresist film. An optical system is set up to characterize the optical performance of the machined microneedle, and then compared with theoretical data. The results show that the length of the microneedle from the experiment is close to the derived results. Moreover, the length of the microneedle is significantly influenced by the height and diameter of the microlens. Therefore, this method could also simplify the process and reduce the time needed for the fabrication of the microneedle. The micro cone microneedle has have great potential in the area of the drug delivery applications.
- 出版日期2015-9
- 单位南开大学
