Nanoantennas as Biomarkers for Bacterial Detection

作者:Shiigi Hiroshi*; Kinoshita Takamasa; Fukuda Maho; Dung Quynh Le; Nishino Tomoaki; Nagaoka Tsutomu
来源:Analytical Chemistry, 2015, 87(7): 4042-4046.
DOI:10.1021/acs.analchem.5b00415

摘要

Understanding the biology of bacteria is critical for exploiting their beneficial properties and for preventing and treating bacterial diseases. Nanobioscience is an area that has recently seen major scientific progress. Here, we demonstrate that a raspberry-shaped nanostructure with a high density of gold nanoparticles acts like an excellent antenna due to its optical properties, which permit sensitive detection and analysis of bacterial cells. By using antibodies, these nanoantennas can be engineered to recognize only specific bacterial species. This system provides a new technique that will allow for more sensitive detection of specific bacteria.

  • 出版日期2015-4-7