科研之友
微信
新浪微博
Facebook
分享链接
摘要
Efficient Cinchona-derived chiral 2-aminobenzimidazole catalysts were prepared by the coupling of 5,7-bis(trifluoromethyl)-2-chlorobenzimidazole with C(9S)-aminodihydroquinine or C(9R)-aminodihydroquinidine and successively applied to the Michael addition of dimethyl malonate to nitroolefins as very efficient chiral Lewis acid bifunctional organocatalysts (up to > 99% ee).
- 出版日期2009-12
- 单位沈阳药科大学
