Dynamic Simulations of Multicomponent Lipid Membranes over Long Length and Time Scales

作者:Camley Brian A*; Brown Frank L H
来源:Physical Review Letters, 2010, 105(14): 148102.
DOI:10.1103/PhysRevLett.105.148102

摘要

We present a stochastic phase-field model for multicomponent lipid bilayers that explicitly accounts for the quasi-two-dimensional hydrodynamic environment unique to a thin fluid membrane immersed in aqueous solution. Dynamics over a wide range of length scales (from nanometers to microns) for durations up to seconds and longer are readily accessed and provide a direct comparison to fluorescence microscopy measurements in ternary lipid-cholesterol mixtures. Simulations of phase separation kinetics agree with experiment and elucidate the importance of hydrodynamics in the coarsening process.

  • 出版日期2010-9-30