Aqueous Heck Arylation of Acrolein Derivatives: The Role of Cyclodextrin as Additive

作者：Al Maksoud Walid; Jahjah Mohamad; Monflier Eric; Ponchel Anne; Leger Bastien; Pinel Catherine^*; Djakovitch Laurent

来源：Topics in Catalysis, 2014, 57(17-20): 1550-1557.

DOI：10.1007/s11244-014-0328-y

• Heck reaction
• Aqueous phase
• Cyclodextrins
• Heterogeneous palladium catalyst
• Cinnamaldehyde
• 3-Arylpropionic esters

Heck arylation of acrolein dialkyl acetal with (hetero)-aryl halides in water catalyzed by solid palladium catalysts and in presence of cyclodextrins is reported. Depending on the nature of the base, either cinnamaldehyde or 3-aryl propionic ester is obtained. It was shown that the presence of cyclodextrins in the reaction media increased the reaction rate as well as the stability of the palladium species.

• 出版日期2014-11