Morphometric Changes in the Dog Trochlear Nerve with Growth

作者：Vivo J^*; Galisteo A M; Miro F; Agueera E; Plaza C; Diz A

来源：Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C , 2013, 42(3): 183-190.

DOI：10.1111/ahe.12001

The objective of this work was to analyse changes in morphometric characteristics related to growth in the trochlear nerve in dogs. Twenty beagles, split into four dog age groups (A, 7days; B, 21days; C, 35days; D, 49days and E, 4years), were used. The right intracranial portion of the nerve was analysed by light and electron microscopy. The nerve cross-sectional area was calculated. Number, diameter and cross-sectional area of unmyelinated and myelinated fibres were also calculated. In myelinated fibres, the corresponding axon area and diameter and myelin sheath thickness were also calculated. The number of myelinated and unmyelinated fibres was 1070.25 +/- 112.07 and 592.25 +/- 467.53 in group A, 1367 +/- 57.98 and 143.67 +/- 54.37 in group B, 1574.20 +/- 299.50 and 151.67 +/- 51.73 in group C, 1340.33 +/- 151 and 127 +/- 48.75 in group D and 1476 +/- 260.71 and 284 +/- 101.82 in group E. The mean diameter for myelinated and unmyelinated fibres was 4.37 +/- 0.17m and 0.41 +/- 0.08m for group A; 6.21 +/- 0.12m and 0.30 +/- 0.03m for B; 6.90 +/- 0.91m and 0.32 +/- 0.03m for C; 7.86 +/- 1.19m and 0.32 +/- 0.02m for D; 10.63 +/- 0.50m and 0.30 +/- 0.01m for E, respectively. This nerve possesses similar structural and ultrastructural features to the same nerve in other species and modifies its morphometry with growth. Results could enhance the understanding of pathological disorders.

• 出版日期2013-6