Double contrast-enhanced ultrasonography for the preoperative evaluation of gastric cancer: A comparison to endoscopic ultrasonography with respect to histopathology

作者：Zheng Zhiqiang; Yu Yaojun; Lu Mingdong; Sun Weijian; Wang Feihai; Li Pihong; Zhang Yi; Lin Limiao; Huang Pingtong; Chen Jianming; Zhang Haiyan; Xie Zuokai; Dong Xiang Da^*

来源：American Journal of Surgery, 2011, 202(5): 605-611.

DOI：10.1016/j.amjsurg.2010.09.033

• Gastric cancer
• Contrast-enhanced ultrasound
• Endoscopic ultrasound
• Staging

BACKGROUND: This study was designed to compare the accuracy of endoscopic ultrasound (EUS) with double contrast-enhanced ultrasound (DCUS) in the staging of gastric malignancies. DCUS is a transabdominal ultrasound technique using both intravenous and intraluminal contrast to enhance sonographic visualization.
METHODS: This retrospective study included 162 patients with biopsy-proven gastric cancer who underwent DCUS and EUS preoperatively with the ultrasound results compared with the pathologic findings of the resected specimens.
RESULTS: The overall accuracy of DCUS and EUS for tumor (T) staging was 77.2% and 74.7%, respectively. Comparison of ultrasound techniques for T staging revealed that DCUS was superior to EUS only for a tumor depth of T3 (chi-square, P = .025). Lymph nodes were staged correctly with DCUS and EUS in 78.4% and 57.4% of cases, respectively (chi-square, P = .001).
CONCLUSIONS: DCUS offers a noninvasive approach for the staging of gastric cancer. DCUS was comparable to EUS in tumor depth evaluation but offered an advantage in lymph node detection.

• 出版日期2011-11
• 单位温州医科大学