Amygdala lesions selectively impair familiarity in recognition memory

作者：Farovik Anja; Place Ryan James; Miller Danielle Renee; Eichenbaum Howard^*

来源：Nature Neuroscience, 2011, 14(11): 1416-1417.

DOI：10.1038/nn.2919

A major controversy in the study of memory concerns whether there are distinct medial temporal lobe (MTL) substrates of recollection and familiarity. Studies using receiver operating characteristics analyses of recognition memory indicate that the hippocampus is essential for recollection, but not for familiarity. We found the converse pattern in the amygdala, wherein damage impaired familiarity while sparing recollection. Combined with previous findings, these results dissociate recollection and familiarity by selective MTL damage.

• 出版日期2011-11