Emergence of five kinds of aminoglycoside-modifying enzyme genes simultaneously in a strain of multidrug-resistant Escherichia coli in China

作者：Wang Sheng Z; Zu Huang M; Xing Bei W^*

来源：Clinical Microbiology and Infection, 2012, 18(1): E11-E12.

DOI：10.1111/j.1469-0691.2011.03710.x

• Aminoglycoside-modifying enzymes
• Escherichia coli
• multidrug resistance
• N-acetyltransferases
• O-nucleotidyltransferases
• O-phosphotransferases

A strain of Escherichia coli was positive for 5 aminoglycoside modifying enzyme genes (aac(3)-I, aac(6')-Ib-cr, ant(3??)-I, aadA5, and aph(3')-I) in PCR assays. And these positive genes confer resistance to aminoglycosides (gentamicin and tobramycin). This is the first report of emergence of five kinds of aminoglycoside-modifying enzymes genes simultaneously in E. coli worldwide.

• 出版日期2012-1
• 单位南京医科大学