A convenient and environmentally benign method of reducing aryl ketones or aldehydes by zinc powder in an aqueous alkaline solution

作者：Zhang Chao-Zhi^*; Wu De-Lin; Yang Hui; Lu Guo-Yuan

来源：Chinese Journal of Chemistry, 2007, 25(5): 653-660.

DOI：10.1002/cjoc.200790122

• aryl ketone
• reduction
• zinc powder
• methylene derivative
• mechanism

A convenient and environmentally benign method for reducing the carbonyl group in hydroxy- and amino-9,10-anthracenediones, ortho (or para) acyl phenols and acyl anilines to a methylene group by zinc powder in an aqueous sodium hydroxide solution was reported. Based on theoretical calculations using the density functional theory (DFT), the mechanism of these reduction reactions was postulated. This mechanism can be applied to help predicting the reduced products of aryl ketones (or aldehydes) in an alkaline solution.

• 出版日期2007-5
• 单位南京大学; 现代配位化学国家重点实验室