A fast, efficient and simple method for the synthesis of cyclic alkenyl fluorides by a fluorinative carbocyclization reaction

作者:Alonso Pedro; Pardo Pilar; Fananas Francisco J*; Rodriguez Felix
来源:Chemical Communications, 2014, 50(92): 14364-14366.
DOI:10.1039/c4cc07376b

摘要

A simple transformation of alkynol or enyne derivatives into cyclic alkenyl fluorides by using tetrafluoroboric acid as the proton and fluoride source is reported. This study includes the first biomimetic cationic cyclization/nucleophilic fluorination reaction of polyenyne derivatives to give terpenoid derivatives.

  • 出版日期2014