科研之友
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摘要
Background: Virtual colonoscopy is a promising new modality for investigating suspected colonic disorders, it is relatively safe, can be done without sedation and in less time compared to conventional colonoscopy. Aim of this work: to evaluate the application of virtual colonoscopy in different indications of conventional colonoscopy and compare between both procedures as regards sensitivity and specificity of both methods, putting the hypothesis that virtual colonoscopy can replace the conventional colonoscopy. Subjects and Methods: a group of eighty two patients having different indications for colonoscopy were included; all patients underwent full medical history, examination and any needed investigations. Patients were scheduled to undergo both conventional and virtual colonoscopy on the same week, both endoscopist and radiologist were unaware of the other report. Results: Both conventional and virtual colonoscopy detected colonic masses in 18 patients, colonic diverticulae in 5 patients and colonic strictures in 2 patients with no missed or false positive results with 100% sensitivity and specificity; and 100% positive and negative predictive values. Meaning that virtual colonoscopy was accurate in detection of masses, diverticulae and strictures. However detection of polyps by virtual colonoscopy was 88% sensitive and 77% specific with 3 missed polyps (small polyps) and 13 false positive polyps detected by virtual colonoscopy. Virtual Colonoscopy Could not detect any of the following lesions: angiodysplasia (2 patients), ulcerative colitis (without pseudo polyps) (3 patients), flat ulcers and non-specific colitis (11 patients), with a Sensitivity 0%. Conclusion: Virtual Colonoscopy can be used in evaluation of patients presenting with constipation, weight loss or abdominal pain in whom colonoscopic examination was indicated (in these patients colonic lesions were masses, strictures and diverticulae, so virtual colonoscopy is sensitive in detecting these lesions). But the use of virtual colonoscopy is limited in patients presenting with anemia and positive occult blood in stools, bleeding per-rectum and chronic diarrhea (in these patients the colonic lesions were angiodysplasia, flat ulcers and non specific colitis, so virtual colonoscopy is not sensitive in detecting these lesions). Also, virtual colonoscopy is a good diagnostic tool for screening for colorectal carcinoma, however using the recent technology in virtual colonoscopy as new faster CT multi-slice machines with the least possible slice thickness in order not to miss a small lesion is recommended. [Wael M. Aref; Ahmed El-Mazny and Farid G. Amin. A Comparative Study between Virtual Colonoscopy (CT Colonoscopy) and Conventional Colonoscopy in Different Presentations of Suspected Colonic Disorders. Life Sci J 2012;9(3):561-567] (ISSN: 1097-8135). http://www.lifesciencesite.com. 79
- 出版日期2012
