An atypical meningioma demystified and advanced magnetic resonance imaging techniques

作者：Voultsinou Despoina; Matis Georgios K^*; Chrysou Olga I; Birbilis Theodossios A; Cheva Angeliki; Geroukis Triantafillos

来源：Journal of Cancer Research and Therapeutics, 2014, 10(2): 387-389.

DOI：10.4103/0973-1482.136666

• Atypical meningioma
• diffusion-weighted imaging
• functional magnetic resonance imaging
• magnetic resonance venography
• magnetic resonance spectroscopy
• perfusion-weighted imaging

A 40-year-old male presented with visuospatial processing disturbances. Family history was free. Conventional and advanced magnetic resonance imaging (MRI) studies were performed. On T2 and fluid attenuation inversion recovery images, an increased signal intensity extra-axial lesion was demonstrated. Post-contrast scans depicted homogeneous intense contrast medium enhancement. T2* star sequence was negative for hemorrhagic or calcification foci. Diffusion-weighted imaging findings were indicative of malignant behavior and magnetic resonance venography confirmed superior sagittal sinus infiltration. Increased cerebral blood volume values were observed and peri-lesional oedema on perfusion-weighted imaging was also demonstrated. The signal intensity-time curve depicted the characteristic meningioma pattern. Spectroscopy showed increased choline and alanine levels, but decreased N-acetyl-aspartate levels. Conventional MRI is adequate for typical types of meningiomas. However, the more atypical ones, in which even the histopathologic specimen may demonstrate characteristics of typical meningioma, could be easier diagnosed with advanced MRI techniques.

• 出版日期2014-6