ACETANILIDE: SOLVENT-FREE GREEN SYNTHESIS

作者:Cunha Silvio*; dos Santos da Costa Otelicio Bispo; Botelho de Santana Lourenco Luis; Lopes Wilson Araujo
来源:Quimica Nova, 2015, 38(6): 874-876.
DOI:10.5935/0100-4042.20150080

摘要

We described herein a solvent-free synthesis of acetanilide developed in the context of green chemistry. The synthetic approach consisted of the reaction of aniline with acetic anhydride without additives, while using smaller amounts of reagents and water than previously described for this undergraduate experiment. The E Factor was 0.6 by experienced chemists and 0.9 by students.

  • 出版日期2015-7

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