A Microfluidic Hydrogel Capable of Cell Preservation without Perfusion Culture under Cell-Based Assay Conditions

作者:Xu Yan*; Sato Kae; Mawatari Kazuma; Konno Tomohiro; Jang Kihoon; Ishihara Kazuhiko; Kitamori Takehiko
来源:Advanced Materials, 2010, 22(28): 3017-3021.
DOI:10.1002/adma.201000006

摘要

A 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer hydrogel exhibits a remarkable ability to preserve cells on microfluidic chips without perfusion culture under cell-based assay conditions, with characteristics of maintenance of high cell viability, restraint of cell proliferation, and minimization of cellular function loss over a period of days and weeks. This would establish a revolutionary flexibility for cell-based applications.

  • 出版日期2010-7-27