科研之友
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摘要
Crataegus songorica leaves collected in different months were extracted by ethanol then partitioned by system solvents with different polarity.The total flavonoids in the ethanol extract,cyclohexane fraction,ethyl acetate fraction,n-butanol fraction and water fraction were measured and the antioxidant activity and in vitro hypoglycemia activity were assayed by scavenging activity of DPPH radicals,reducing power and anti-α-glucosidase activity.The results showed that different extracts from Crataegus songorica leaves all exhibited different degree of antioxidant activity and anti-cα-glucosidase activity,among which ethyl acetate fraction showed strong activity.The ethyl acetate fraction had 28.87 mg/g of total flavonoids and its IC50 of DPPH assay was 0.026 mg/mL while the IC50 of anti-α-glucosidase activity was 191.71 g/mL,it was far higher than that of the positive control BHA(IC50 =0.996 mg/mL) and acarbose(IC50 =1 044.32 g/mL).The antioxidant and antiα-glucosidase activities of the extracts were positively correlated to their total flavonoids,it showed that flavonoids were main factors for the activities.
- 出版日期2017
- 单位伊犁师范大学
