Ultrasensitive Detection of Enrofloxacin in Chicken Muscles by Surface-Enhanced Raman Spectroscopy Using Amino-Modified Glycidyl Methacrylate-Ethylene Dimethacrylate (GMA-EDMA) Powdered Porous Material

作者：Xu, Ying; Du, Yiping^*; Li, Qingqing; Wang, Xuan; Pan, Yingcheng; Zhang, Han; Wu, Ting; Hu, Huilian

来源：Food Analytical Methods, 2014, 7(6): 1219-1228.

DOI：10.1007/s12161-013-9736-z

• Enrofloxacin
• Surface-enhanced Raman spectroscopy
• GMA-EDMA powdered porous material
• Ultrasensitive detection
• Chicken muscles

Illegally use of enrofloxacin in chicken has raised serious concerns due to its negative effects on public health. In this study, surface-enhanced Raman spectroscopy (SERS) using amino-modified glycidyl methacrylate-ethylene dimethacrylate (GMA-EDMA) powdered porous material was developed and validated to detect enrofloxacin in chicken muscles. By this method, enrofloxacin in chicken muscles was successfully detected at a concentration of 0.01 mg kg(-1), which was lower than the legal maximum residue limit. And the unique "fingerprint-like" spectral patterns of enrofloxacin obtained from SERS spectra could be used for identification and characterization. Compared with high-performance liquid chromatography, the assay of six samples with SERS was rapid in less than 40 min, and the detection was highly sensitive. The results demonstrate that SERS using GMA-EDMA powdered porous material can be potentially employed as a screening tool for rapid detection of residual drugs in a large amount of food samples.

• 出版日期2014-7
• 单位华东理工大学